Screwed things up把事情搞砸

screw sb up 使（某人）焦慮不安，令（某人）很難過；使（某人）精神崩潰。
如screw v. 將（尤指紙或布）揉成團。出現screw sth up也要結合句意。
to twist and crush something, especially paper or cloth, roughly with your hands
 
【例句】
I totally screwed up the chemistry exam.
化學考試被我徹底考砸了。
 
It really screwed him up when he saw his friend get killed.
看到自己的朋友遇難，他傷心欲絕。
 
She screwed the bag up and threw it in the bin.
她把包揉成一團，扔進了垃圾筒。